Eotaxin Antibody / CCL11

Information
Catalog numberR32127
NameEotaxin Antibody / CCL11
Size0.1mg
Price406.00 EUR
SupplierNJS poly
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Extended details
CategoryAntibody
Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenEotaxin / CCL11
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivityHuman (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Tested applicationsWB, ELISA
Recommended dilutionsWestern blot: 0.1-0.5ug/ml,ELISA : 0.1-0.5ug/ml
NotesOptimal dilution of the CCL11 antibody should be determined by the researcher.
Intented useThis CCL11 antibodyis to be used only for research purposes and not for diagnostics..
Uniprot #P51671
PurityAntigen affinity
DescriptionCCL11 (Chemokine (C-C motif) ligand 11), also known as Eotaxin, is a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxin is a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
ImmunogenAmino acids 24-97 of human Eotaxin/CCL11 were used as the immunogen for the CCL11 antibody.
StorageAfter reconstitution, the CCL11 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps