Eotaxin Antibody

Information
Catalog numberR30607
NameEotaxin Antibody
Size0.1mg
Price389.00 EUR
SupplierNJS poly
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Extended details
CategoryAntibody
Concentration0.5mg/ml if reconstituted with 0.2ml sterile DI water
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenEotaxin
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivityMouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Tested applicationsWB
Recommended dilutionsWestern blot: 0.5-1ug/ml
NotesThe stated application concentrations are suggested starting amounts. Titration of the Eotaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Intented useThis Eotaxin antibodyis to be used only for research purposes and not for diagnostics..
Uniprot #P48298
PurityAntigen affinity
DescriptionEotaxin, also known as CCL11(Chemokine(C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1(CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
ImmunogenAn amino acid sequence from the C-terminus of mouse Eotaxin (CADPKKKWVQDATKHLDQKLQ) was used as the immunogen for this Eotaxin antibody (100% rat homology).
StorageAfter reconstitution, the Eotaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
PropertiesIf you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps