Eotaxin Antibody

Catalog numberPB9065
NameEotaxin Antibody
Size0,1 mg
Price374.00 EUR
Extended details
Target antigenEotaxin
ClonalityPolyclonal antibody
ClonePolyclonal antibody
Raised inrabbit
Type of the antibodyIgG polyclonal antibody
Product formfreeze-dried
Reacts with species:human, mouse, rat
ImmunogenE.coli-derived mouse Eotaxin recombinant protein (Position: H24-P97). Mouse Eotaxin shares 62% and 97% amino acid (aa) sequences identity with human and rat Eotaxin, respectively.
Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
PurificationImmunogen affinity purified.
SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
Storage condtionsKeep the Eotaxin Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
TipsThe Eotaxin Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
BackgroundCCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3(CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. CCL11 is a small cytokine belonging to the CC chemokine family. It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor.
Related articles1. Ogilvie, P.; Bardi, G.; Clark-Lewis, I.; Baggiolini, M.; Uguccioni, M. Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5. Blood 97: 1920-1924, 2001. 2. Hein, H.; Schluter, C.; Kulke, R.; Christophers, E.; Schroder, J.-M.; Bartels, J. Genomic organization, sequence, and transcriptional regulation of the human eotaxin gene. Biochem. Biophys. Res. Commun. 237: 537-542, 1997.
Gene NameCCL11
Protein NameEotaxin
Gene Full Namechemokine (C-C motif) ligand 11
SynonymsC-C motif chemokine 11 antibody|CCL 11 antibody|CCL11 antibody|CCL11_HUMAN antibody|chemokine (C-C motif) ligand 11 antibody|Chemokine C C motif ligand 11 antibody|Chemokine CC Motif Ligand 11 antibody|Chemokine ligand 11 antibody|Eosinophil chemotactic protein antibody|Eotaxin antibody|eotaxin-1 antibody|MGC22554 antibody|SCYA 11 antibody|SCYA11 antibody|Small inducible cytokine A11 antibody|Small inducible cytokine subfamily A (Cys Cys) member 11 antibody|small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) antibody|Small inducible cytokine subfamily A member 11 antibody|Small-inducible cytokine A11 antibody
Uniprot IDP48298
Entrez GeneID20292
PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translationanticorps