Information
| Catalog number |
PKSH032186-10µg |
| Name |
Recombinant Human C-C Motif Chemokine 11/CCL11/Eotaxin Protein |
| Size |
10µg |
| Price |
210.00 EUR |
| Supplier |
Elabscience
|
|
Order
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| Synonym |
Eotaxin; C-C Motif Chemokine 11; Eosinophil Chemotactic Protein; Small-Inducible Cytokine A11; CCL11; SCYA11 |
| Activity |
NA |
| Sequence |
Gly24-Pro97 |
| Fusion tag |
NA |
| Accession |
P51671 |
| Expressed Host |
E.coli |
| Shipping |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| Purity |
＞95% as determined by reducing SDS-PAGE. |
| Endotoxin |
＜1.0 EU per µg as determined by LAL test. |
| Stability and Storage |
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months |
| Mol Mass |
8.6 kDa |
| AP Mol Mass |
14 kDa |
| Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl，pH7.4. |
| Background |
C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. |
| Description |
Chemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by Elabscience in 1. |
| Properties |
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples. |
| Source |
Recombinants or rec. proteins |
| Group |
recombinants |