Recombinant Human C-C Motif Chemokine 11/CCL11/Eotaxin Protein

Information
Catalog numberPKSH032186-10µg
NameRecombinant Human C-C Motif Chemokine 11/CCL11/Eotaxin Protein
Size10µg
Price210.00 EUR
SupplierElabscience
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Extended details
SynonymEotaxin; C-C Motif Chemokine 11; Eosinophil Chemotactic Protein; Small-Inducible Cytokine A11; CCL11; SCYA11
ActivityNA
SequenceGly24-Pro97
Fusion tagNA
AccessionP51671
Expressed HostE.coli
ShippingThe product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Purity>95% as determined by reducing SDS-PAGE.
Endotoxin<1.0 EU per µg as determined by LAL test.
Stability and StorageLyophilized protein should be stored at <-20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at <-20℃ for 3 months
Mol Mass8.6 kDa
AP Mol Mass14 kDa
FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl,pH7.4.
BackgroundC-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.
DescriptionChemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by Elabscience in 1.
PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
SourceRecombinants or rec. proteins
Grouprecombinants