Information
| Catalog number |
R32127 |
| Name |
Eotaxin Antibody / CCL11 |
| Size |
0.1mg |
| Price |
406.00 EUR |
| Supplier |
NJS poly
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Order
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| Category |
Antibody |
| Concentration |
0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Form |
Antigen affinity purified |
| Conjugation |
Unconjugated |
| Clone |
Polyclonal antibody |
| Recognised antigen |
Eotaxin / CCL11 |
| Host animal |
Rabbit (Oryctolagus cuniculus) |
| Clonality |
Polyclonal (rabbit origin) |
| Species reactivity |
Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur. |
| Tested applications |
WB, ELISA |
| Recommended dilutions |
Western blot: 0.1-0.5ug/ml,ELISA : 0.1-0.5ug/ml |
| Notes |
Optimal dilution of the CCL11 antibody should be determined by the researcher. |
| Intented use |
This CCL11 antibodyis to be used only for research purposes and not for diagnostics.. |
| Uniprot # |
P51671 |
| Purity |
Antigen affinity |
| Description |
CCL11 (Chemokine (C-C motif) ligand 11), also known as Eotaxin, is a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxin is a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1 (CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12. |
| Immunogen |
Amino acids 24-97 of human Eotaxin/CCL11 were used as the immunogen for the CCL11 antibody. |
| Storage |
After reconstitution, the CCL11 antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing. |
| Properties |
If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| French translation |
anticorps |