Eotaxin Antibody

Catalog number R30607
Name Eotaxin Antibody
Size 0.1mg
Price 389.00 EUR
Supplier NJS poly
Extended details
Category Antibody
Concentration 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Form Antigen affinity purified
Conjugation Unconjugated
Clone Polyclonal antibody
Recognised antigen Eotaxin
Host animal Rabbit (Oryctolagus cuniculus)
Clonality Polyclonal (rabbit origin)
Species reactivity Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
Tested applications WB
Recommended dilutions Western blot: 0.5-1ug/ml
Notes The stated application concentrations are suggested starting amounts. Titration of the Eotaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Intented use This Eotaxin antibodyis to be used only for research purposes and not for diagnostics..
Uniprot # P48298
Purity Antigen affinity
Description Eotaxin, also known as CCL11(Chemokine(C-C motif) ligand 11), a small cytokine belonging to the CC chemokine family. Eotaxin selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of Eotaxin are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which Eotaxinis a ligand include CCR2, CCR3 and CCR5. However, it has been found that eotaxin-1(CCL11) has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3. The gene for human Eotaxin is encoded on three exons and is located on chromosome 17q12.
Immunogen An amino acid sequence from the C-terminus of mouse Eotaxin (CADPKKKWVQDATKHLDQKLQ) was used as the immunogen for this Eotaxin antibody (100% rat homology).
Storage After reconstitution, the Eotaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
Properties If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps