Information
| Catalog number |
PB9065 |
| Name |
Eotaxin Antibody |
| Size |
0,1 mg |
| Price |
374.00 EUR |
| Supplier |
boster
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Order
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| Target antigen |
Eotaxin |
| Clonality |
Polyclonal antibody |
| Clone |
Polyclonal antibody |
| Raised in |
rabbit |
| Type of the antibody |
IgG polyclonal antibody |
| Product form |
freeze-dried |
| Reacts with species: |
human, mouse, rat |
| Analyses |
WB |
| Immunogen |
E.coli-derived mouse Eotaxin recombinant protein (Position: H24-P97). Mouse Eotaxin shares 62% and 97% amino acid (aa) sequences identity with human and rat Eotaxin, respectively. |
| Product configuration |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
| Purification |
Immunogen affinity purified. |
| Solubilization |
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml |
| Storage condtions |
Keep the Eotaxin Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way. |
| Tips |
The Eotaxin Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics. |
| Background |
CCL11, also known as Eotaxin, is a potent inducer of eosinophil chemotaxis and is considered as a selective ligand of the CC chemokine receptor 3(CCR3), which is expressed on eosinophils, basophils, and Th2 lymphocytes. The gene maps to chromosome 17 and is expressed constitutively at high levels in small intestine and colon, and at lower levels in various other tissues. CCL11 is a small cytokine belonging to the CC chemokine family. It is assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. |
| Related articles |
1. Ogilvie, P.; Bardi, G.; Clark-Lewis, I.; Baggiolini, M.; Uguccioni, M. Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5. Blood 97: 1920-1924, 2001. 2. Hein, H.; Schluter, C.; Kulke, R.; Christophers, E.; Schroder, J.-M.; Bartels, J. Genomic organization, sequence, and transcriptional regulation of the human eotaxin gene. Biochem. Biophys. Res. Commun. 237: 537-542, 1997. |
| Gene Name |
CCL11 |
| Protein Name |
Eotaxin |
| Gene Full Name |
chemokine (C-C motif) ligand 11 |
| Synonyms |
C-C motif chemokine 11 antibody|CCL 11 antibody|CCL11 antibody|CCL11_HUMAN antibody|chemokine (C-C motif) ligand 11 antibody|Chemokine C C motif ligand 11 antibody|Chemokine CC Motif Ligand 11 antibody|Chemokine ligand 11 antibody|Eosinophil chemotactic protein antibody|Eotaxin antibody|eotaxin-1 antibody|MGC22554 antibody|SCYA 11 antibody|SCYA11 antibody|Small inducible cytokine A11 antibody|Small inducible cytokine subfamily A (Cys Cys) member 11 antibody|small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) antibody|Small inducible cytokine subfamily A member 11 antibody|Small-inducible cytokine A11 antibody |
| Uniprot ID |
P48298 |
| Entrez GeneID |
20292 |
| Properties |
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. |
| French translation |
anticorps |